If you're hanging out in the neighborhood this weekend, keep your eyes peeled for Hugh Laurie. The new Hulu show Chance—starring Laurie as a doctor who falls into the city's seedy underbelly—is set to continue filming around the Tenderloin and Civic Center this weekend.

According to signs posted around the neighborhood, the crew will be closing down Fulton Street between Larkin and Hyde (aka Marshall Square) for its basecamp from 4am Saturday, April 30th to 8am Tuesday, May 3rd. The actual filming will take place from 7am-10pm Sunday, May 1st and Monday, May 2nd.