On January 20, 2018, Women's March San Francisco united with multiple cities around the world to reaffirm the commitment to building a positive and just future for all, and to celebrate the spirit of resistance efforts over the past year. 

It began with a rally at Civic Center, designed to engage and empower all people supporting intersectional feminism, women's rights, human rights, civil rights, disability rights, LGBTQIA rights, workers rights, immigrant rights, reproductive, social and environmental justice. 

In 2017, an estimated 100,000 people marched from Civic Center to the Embarcadero to protest incoming president Donald Trump on inauguration day. The route for the 2018 march was the same: starting at Civic Center Plaza then the official march headed down Market Street to the Embarcadero near the Valliancourt Fountain.