A six-month-old Alaska baby became the youngest CHOP patient to receive gene therapy for metachromatic leukodystrophy. His case underscores the race to diagnose MLD before symptoms begin.

A Pentagon budget fight could put thousands of Delaware County jobs tied to Boeing's Chinook line at risk.

A Lansdale daycare worker is accused of kicking multiple children, including one who suffered a fractured ankle. Investigators also say classroom surveillance videos were deleted.

A 16-year-old was shot in the neck Sunday on the 4700 block of Tackawanna Street in Frankford and remains in stable condition at Temple University Hospital.

The Eagles extended Jalen Carter to a four‑year, $152M deal with $106M guaranteed, making him the NFL's highest‑paid defensive tackle as training camp opened. The move locks in Philly's interior line.

Inspectors flagged 156 violations at All American Gardens in Camden; reinspections are planned while tenants report mold, pests and electrical hazards.

River Twice is expanding into the former Manatawny tasting‑room space on East Passyunk, adding a 13‑seat bar, 24 new seats and an à la carte menu while keeping its tasting‑menu core.

A 27-year-old man was shot during a reported domestic incident in Allen Township and later died; a 25-year-old suspect was arrested after a brief pursuit.

A Wilmington stylist allegedly pepper-sprayed a client and her parents after a price dispute; two were treated at a hospital and the stylist was charged and released on bail.

Monell is moving up the street: the taste‑and‑smell research institute signed a 20‑year lease at One uCity Square and plans to relocate its labs and staff in early 2027.

A Chester County man died after his car collided head-on with a FedEx truck in Richmond Township; the coroner ruled the death accidental.

More than 100 people gathered at Philadelphia City Hall for a candlelit vigil after two recent ICE‑involved killings; organizers demanded investigations and policy changes.

Police and state troopers responded to Norristown State Hospital Friday morning; Pennsylvania State Police is investigating and there were no immediate reports of injuries. Chopper 6 footage showed crime tape and a red vehicle in the lot.