Duke and other labs are testing drugs and mitochondrial therapies that could ease chronic pain without sparking opioid addiction.

Low 90s today; mid-to-upper 90s this weekend and a chance of triple-digit heat by Wednesday.

A late-night argument on Emily Lane near Oxford turned into a shootout Monday night; deputies say one person was killed and three others injured as investigators detained multiple people.

The State Board of Elections will rehear a complaint June 24 over Wake County counting three early ballots cast by voters who died before Election Day 2024.

NWS warned of fast-moving storms across Robeson and Bladen counties Tuesday, with gusts up to 40 mph and travel impacts on I‑95.

A rebuilt Eastman Leadership Academy has opened in Enfield — a 101,000‑sq‑ft campus built largely with $48.5M in lottery grants and nearly $53M in total cost.

Strong storms toppled trees and left nearly 1,000 Duke Energy customers in Granville County without power, with the worst damage near Highway 96 outside Oxford.

A Cary resident hit the $100,000 top prize on a $30 Cash Payday scratch-off and claimed $72,018 after taxes.

A 13-year-old passenger was killed after a Ford F‑350 blew a tire and overturned on I‑540 near the Neuse River Bridge. The driver now faces misdemeanor charges.

Hundreds queued at Dick's Sporting Goods in Cary on Father's Day to meet Hurricanes forward Seth Jarvis as the team's Stanley Cup festivities continued.

A 33-year-old driver was killed after an SUV crossed the centerline and struck a pickup on N. Roxboro Street early Sunday; investigators are asking witnesses to come forward.

The North Carolina House approved HB1029 to let state‑chartered banks custody crypto and create a licensing path for payment stablecoins, with strict reserve and audit rules.

The NC SBI says former Madison County chief deputy Bronis Coy Phillips was arrested in Arizona and is being held without bond pending extradition. The probe involves alleged criminal activity with inmates and detention‑facility staff.