Greyhound is moving out of its long-standing downtown Houston location to set up shop at a new depot at 7000 Harrisburg Blvd., starting Thursday. The iconic bus company confirmed the big move, waving goodbye to its 2121 Main St. home that has stood since 1990, as reported by the Houston Chronicle.

The new East End location is at the end of the Metropolitan Transit Authority’s Green Line light rail and steps from the Magnolia Park Transit Center. A handful of smaller bus carriers, many of which serve Mexico, operate in the vicinity.  Greyhound's Gilda Brewton sings praises about the Harrisburg Boulevard location, asserting, "The Houston market remains one of the most important in the country for Greyhound," in a statement obtained by the Houston Chronicle.

Midtown's Greyhound site, according to Harris Central Appraisal District records at $8 million as of January 1, 2023, is now in the realtor's hands, with Cushman & Wakefield holding the reins on the market.

Travelers looking to hit the road with Greyhound can still snag tickets 24/7 at the new depot.