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UTMB Leads Advances in Personalized Medicine with Novel Mechanobiology-Based Device for Thrombosis Risk Assessment

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Published on January 03, 2025
UTMB Leads Advances in Personalized Medicine with Novel Mechanobiology-Based Device for Thrombosis Risk AssessmentSource: Google Street View

Researchers at the University of Texas Medical Branch are using mechanobiology to improve the diagnosis of thrombotic risks, advancing the fight against cardiovascular diseases. Dr. Yunfeng Chen, an assistant professor at UTMB, leads the study, which uses a miniaturized device to simulate narrowed arteries in order to better assess an individual’s risk for arterial thrombosis. The study was recently published in Nature, as per University of Texas Medical Branch News release.

The technique explores how blood behaves under the physical constraints of narrowed arteries, which can lead to arterial thrombosis—the formation of clots that contribute to global health issues. The device aims to help clinicians provide more accurate assessments of thrombotic risks. Dr. Chen explained in the same release, "In this study, we're trying to see how mechanobiology could help researchers and clinicians make better diagnosis of the thrombotic risks, especially the risk of arterial thrombosis that are closely associated with cardiovascular diseases."

Dr. Chen also shared details about the device’s operation in a recent video, inviting medical professionals and academics to learn about the science behind it. 

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