A trial opens Monday to decide whether animal-rights groups can block rodeos at Petco Park as past horse injuries and sponsor withdrawals loom over the case.

A suspected DUI crash in El Cajon sent a mother and two small children to hospitals; police arrested the driver at the scene.

A 94-year-old Clairemont woman was seriously injured after a BMW struck her in a crosswalk; police say the Traffic Division is investigating.

On Saturday, San Diegans gathered in Pacific Beach and El Cajon as part of nationwide 'ICE Out' actions after the Minneapolis shooting. A new photo gallery shows local turnout and chants.

San Diego is set to experience moderate to strong Santa Ana winds with rising temperatures, particularly affecting coastal slopes and inland valleys. Winds are expected to weaken but stay strong into the week, with warm days ahead.

An FBI search-warrant operation in Chula Vista turned into a lengthy standoff; an individual inside was later found unresponsive and officials have not released details.

Pastry chef Arely Chavez has debuted Amor, a small-batch ice cream project serving Mexican-inspired flavors at neighborhood pop-ups around San Diego.

A new 60,000‑square‑foot facility in Vista gives the San Diego Food Bank a permanent North County base and a grocery‑style client‑choice pantry.

A 41-year-old man was arrested after a months-long probe into the Aug. 11 Chula Vista crash that overturned an SUV and killed two. He faces suspicion of vehicular manslaughter and reckless driving.

San Diego Humane Society plans to convert a tiny on‑campus clinic into an $11M donor‑funded hospital to expand low‑cost care and keep pets out of shelters.

CIRM awarded $7.4M to a UC San Diego team to complete preclinical safety, off‑target testing and manufacturing scale‑up for a CRISPR‑edited stem‑cell therapy for Friedreich’s ataxia.

Anaergia won a design‑build contract to build a biopower plant that will convert treatment‑plant organics into electricity for the East County AWP, aimed at cutting costs and supplying a chunk of the plant's power.

A UC San Diego‑led paper finds pharmacists and female pharmacy technicians face elevated suicide risk, with researchers pointing to workplace stress and gaps in care.