Syntax Bio's Science Advances paper introduces 'Cellgorithm', a CRISPR-based method that the company says can shrink stem-cell differentiation from months to days. The approach could speed regenerative therapies if it scales.

A Nixon Peabody-led study finds some Loop office buildings could be converted into housing without upfront city subsidies — but the math is tight and local rules matter.

Credit Union 1 Amphitheatre will require separate parking passes for 2026 shows; general lots will cost about $20–$25 and premium options will be pricier.

Sonic Speed Cafe arrives in Wicker Park on Dec. 20 with chili dogs, a chef-curated menu and Chicago-only merch. The pop-up will feature a local mural and limited run.

A 29-year-old man, Joel Quintero Cristian, was charged with first-degree murder in Chicago following the fatal shooting of a 28-year-old woman. His detention hearing is set for December 10, 2025.

Two off-duty deputies were shot at near Mount Sinai Hospital in Chicago; neither was hurt, bullets hit their vehicle. The incident is under investigation. No arrests yet.

Early morning shooting on I-57 near Calumet Park prompted Illinois State Police to close northbound lanes; no injuries reported, investigation ongoing.

Workers at the Chicago Botanic Garden have intensified a union drive while county officials weigh in and management resists card‑check recognition.

A man was shot and killed by Chicago police investigating a stolen car; an officer was dragged by the vehicle as the suspect tried to flee and subsequently fired at him.

Anthony Brown was sentenced to 33 years for his role in a Lombard tobacco shop armed robbery and shootout, which injured an officer and led to his accomplice's death.

Chicago is expecting snow and strong winds on Wednesday morning, leading to a challenging commute, with less than an inch of snow but high winds persisting into the evening. Further cold and snow are forecasted for the weekend.

An SUV crashed into an East Peoria Dollar General store without causing injuries. The facade was damaged but the structure remained intact. The cause is under investigation and cleanup efforts are underway.

An Elgin man, Luis Jesus Acosta Gutierrez, was arrested after a standoff with ICE, with DHS claiming he has gang ties and caused a car crash. No ICE injuries occurred, and Elgin police's non-involvement followed local law, causing some controversy.