David Fajgenbaum was hospitalized without a diagnosis for nearly seven weeks during his first Castleman disease episode before finding his own treatment — now his nonprofit scans old drugs for new cures.

One injured person was taken to University of Chicago Medical Center, another to Crown Point, after a head-on wreck shut down I-65 for hours.

A fall at the Lakeview clinic sent someone to the hospital in fair-to-serious condition, fire officials say.

Anthony Anderson hosts the Nov. 5 Harris Theater taping as Chaka Khan, a Chicago native, gets the Classic Soul Honor.

Alciro Deacon, a Milwaukee minister and state contract administrator, is taking on Assembly Assistant Minority Leader Kalan Haywood.

Ricardo Perez, 35, evaded deputies for eight months and five days before a dropped cellphone cracked the case.

A foundation permit clears the way for a five-story project at 4920 N. Sheridan, with a rooftop deck for every renter.

Portage officials toured Roanoke and Grand Prairie, Texas, hunting ideas for a family attraction and a walkable downtown near Portage Mall.

Osho Market on South Archer Avenue lost its ATM before dawn Sunday. No one was hurt, but police are still hunting the crew.

A former South Side motel is being converted into 26 private units for homeless young adults.

Colleen Maher once sat in these Rockford classrooms as a toddler. Now she helps a nonverbal student find his voice.

Endeavor Hotels scooped up seven hotels and a TGI Friday's near Midway for $68 million, borrowing $90 million to close the deal.

A woman was found naked and unresponsive on North Wolcott; one suspect was already out on a meth and heroin case.