A San Diego biotech is moving an investigational gout drug through late-stage trials, backed by $130 million in new financing.

A 30-year-old man was arrested after an attempted carjacking at the Massachusetts Avenue trolley station in Lemon Grove; deputies say the passenger was uninjured.

An extreme heat warning covers the San Diego County mountains this week, with highs into the mid‑90s–105°F. Officials urge hydration, rest breaks and Cool Zones for vulnerable residents.

Police say a stolen excavator rolled through North Park Monday before an arrest followed. The kind of street drama that turns a neighborhood into a headline.

A new federal law removes the permanent chassis rule for manufactured homes, a change that could cut thousands off new units — but San Diego zoning, land and lending may limit local impact.

San Diego’s county average rose to $5.717 per gallon on July 26, adding roughly 27.8 cents in 12 days as regional refinery issues and global oil volatility push pump prices higher.

San Diego members of Congress unveiled twin bills to ease IVF bills: one would require TRICARE to cover fertility care for military families, the other lets people use retirement funds penalty‑free for treatment.

Joe Harper will retire as Del Mar's CEO at year's end after nearly 50 years with the track. Josh Rubinstein will take over as CEO on Jan. 1, 2027.

Heat Advisory through Monday with sticky coastal nights and 3–6 ft surf. County Cool Zones are open; avoid rip currents and stay hydrated.

Heat Advisory for San Diego coast through Monday with warm afternoons and muggy nights. Expect higher surf and stronger rip currents.

A 99-year-old woman was struck and killed by an SUV on the 6400 block of Cleo Street in San Diego’s College area, police say.

Patchy fog this morning clears to mostly sunny skies and highs near 83°F. Heat Advisory and Beach Hazards Statement will affect the coast through the weekend.

Mayor Todd Gloria says Comic‑Con will remain in San Diego through 2030, extending past the city's previous 2027 pact. The announcement has big implications for hotels and downtown businesses.