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North Carolina Rolls Out Wildlife Rabies Vaccination Program in Western Counties to Protect Public Health

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Published on September 29, 2025
North Carolina Rolls Out Wildlife Rabies Vaccination Program in Western Counties to Protect Public HealthSource: Unsplash/ Jason Dean Chamberlain

North Carolina's Department of Health and Human Services, in collaboration with the U.S. Department of Agriculture, is rolling out its annual wildlife oral rabies vaccination effort. The program, set to commence on October 16, is primarily targeted at immunizing wild raccoons against the deadly virus in western regions of the state, aiming to protect both the human and pet populations, as reported by the NCDHHS.

Residents of Ashe, Avery, Buncombe, Cherokee, Clay, Graham, Haywood, Henderson, Jackson, Macon, Madison, Mitchell, Swain, Transylvania, Watauga, and Yancey counties may observe the aerial distribution of oral rabies vaccine baits. This approach is part of a longstanding strategy dating back to the 1990s, originally implemented to prevent the spread of raccoon rabies into areas west of the Appalachian Mountains—regions that have remained free of this particular rabies strain. "The best way to prevent rabies is to avoid contact with wild animals and ensure pets are vaccinated against rabies," Emily Herring, NCDHHS Public Health Veterinarian, emphasized in a press release.

The vaccine works by enclosing it in a sachet or plastic packet inside a bait. When a raccoon consumes the bait, the vaccine is released into its mouth, stimulating an immune response that produces antibodies to protect against rabies. These baits are coated with fishmeal or contained within fishmeal-polymer blocks to attract raccoons. The USDA Wildlife Services recommends leaving the baits undisturbed if found, unless they appear in areas less frequented by raccoons, such as lawns or driveways, in which case they should be carefully moved to areas with denser coverage.

These interventions are considered safe for humans and non-target wildlife, with pets generally at low risk when encountering the baits, although ingestion of multiple packets may cause stomach upset. The USDA advises that the baits may have a noticeable fishmeal odor and recommends using gloves or a towel when handling or relocating them. The NCDHHS release coincides with World Rabies Day on September 28, an event aimed at raising global awareness about rabies prevention. Data from 2024 indicates that about 6% of the 4,000 animals tested in North Carolina were rabies positive, with raccoons representing the majority of cases, highlighting the ongoing need for the vaccination program.

While the oral rabies vaccine is considered safe for both dogs and cats, it is currently approved only for use in wildlife. Therefore, the NCDHHS recommends that household pets continue to receive regular rabies vaccinations administered by licensed veterinarians, which are required by state law starting at four months of age and at designated intervals thereafter. Weather permitting, the vaccine distribution is expected to be completed by the end of October, after which Wildlife Services will continue monitoring raccoon populations and any new cases of rabies.