St. Louis

Double-Life Dining as Jekyll & Hyde Sets Up Split-Personality Spot In Delmar Loop

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Published on May 08, 2026
Double-Life Dining as Jekyll & Hyde Sets Up Split-Personality Spot In Delmar LoopSource: Google Street View

Delmar Loop is about to get a restaurant with a serious split personality. Jekyll & Hyde, a two-level concept that stacks a colorful Mexican-Latin spot on top of a reservations-first steakhouse, is set to open this month at 6100 Delmar. The 4,800-square-foot corner space, formerly home to Prime 55, will lean bright and buzzy upstairs and moody and intimate below, with soft openings in mid-May and a tentative grand opening on May 22.

Opening timeline and location

According to St. Louis Magazine, the team behind Amigo Sole is rolling out soft openings in mid-May, with May 22 circled as the planned grand opening date. The outlet reports that Jekyll & Hyde fills the 4,800-square-foot space at 6100 Delmar, on the prominent corner that once housed Prime 55.

Jekyll — Mexican-Latin upstairs

Upstairs at Jekyll, the focus is on modern Mexican-Latin small plates and a cocktail lineup that includes a tequila old fashioned alongside lighter specialty drinks, per the posted menu from Jekyll & Hyde. The shareable dishes include flame-grilled oysters, shrimp embarazados, fajitas, and Jekyll wings, with the room designed as a bright, social hangout. Sample menus and a reservation link are already live on the restaurant’s site.

Hyde — the underground steakhouse

Head downstairs and the vibe flips. Hyde is billed as “a shadowed, intimate setting” and operates as a reservations-first steakhouse featuring prime and Wagyu cuts, signature starters, and theatrical dessert cocktails, according to Jekyll & Hyde. The steakhouse menu leans into classic sides, tableside flourishes, and a craft-cocktail program designed to pair with those premium steaks.

The team and the concept

Jekyll & Hyde is described as a sibling concept to Amigo Sole. Co-owner Juan Sevilla explains that the three-concept strategy “offers a tier for every budget and demographic—all under one roof,” in an interview with St. Louis Magazine. Marketing manager Rose Hart tells the outlet that Jekyll is meant to feel “fun, vibrant, exciting, and energetic,” while the piece also notes that executive chef Brian Layton brings more than 25 years of fine-dining experience to the kitchen.

What it means for the Loop

The Delmar Loop keeps adding new food and entertainment options, keeping the six-block stretch busy from daytime foot traffic through late-night crowds. Jekyll & Hyde folds into that mix with a multi-tiered setup that aims to catch everything from casual drinkers upstairs to reservation-driven steakhouse regulars downstairs.

Reservations and visiting

Menus and online reservations are being rolled out as the team hosts friends-and-family previews during soft opening service ahead of the official launch. Prospective diners should check the restaurant’s website or local listings for the most up-to-date reservation times and opening details.