A chain-reaction crash on I-5 near Camp Pendleton involving two vehicles and four motorcycles resulted in three fatalities and five injuries, causing significant traffic disruption.

Six arrested in Escondido for a fatal stabbing last month, with the suspects facing murder and assault charges. The crime is believed to be gang-related.

San Diego International Airport prepares for the busiest summer since 2019 and advises travelers to expect delays and arrive early due to construction and high passenger volumes.

A car crash off state Route 905 in Otay Mesa resulted in one fatality and another person injured. Firefighters used extraction tools to free the victims. The cause is under investigation.

San Diego health officials warn of high bacteria levels at some beaches, leading to advisories and closures including Ocean Beach’s Dog Beach and parts of Mission Bay and La Jolla.

A study at UC San Diego School of Medicine found the diabetes drug tirzepatide to be effective in treating obstructive sleep apnea, reducing breathing disruptions better than a placebo.

The U.S. Attorney's Office and FBI have regained over $3 million for elderly fraud victims in San Diego through a coordinated operation involving 40+ asset seizures totaling $5.6 million.

A woman faces charges after a fatal car accident in Del Mar, where a man died following a collision with a tree and a parked vehicle. The driver fled but was later apprehended.

Southern California is set to experience a warm weekend with temperatures 5-10 degrees above average inland, while coastal areas will remain cooler. A Heat Advisory is in effect for certain regions.

Le Coq, a French-style steakhouse by Chef Tara Monsod, opens in La Jolla, bringing modern French cuisine with a Southern California twist. Monsod is San Diego's first James Beard finalist.

The San Diego County Sheriff's Department is investigating the death of a two-month-old baby found unresponsive in an SUV and reminds the public of the importance of car safety for children.

Dr. Wilma Wooten retired as San Diego County’s Public Health Officer after nearly two decades of service and significant contributions, especially during the COVID-19 pandemic.

Three people have been arrested for targeting elderly women in a series of purse snatchings at San Diego County supermarkets, with the DA's Office urging vigilance.