Cloudy morning gives way to partly sunny afternoons with highs near 74°F. NWS warns 4–6 ft surf and strong rip currents through Thursday.

A 50-year-old San Diego man was fatally injured in a multi-vehicle crash on Iris Avenue in the Nestor neighborhood and later died at UCSD Hillcrest, officials say.

Cloudy morning clears to sun with highs near 73°F. Warming through midweek, with inland and desert areas seeing higher heat.

Solutions for Change repaid more than $500,000 to replenish housing reserve accounts and named Aaron Byzak CEO amid an audit and leadership dispute.

San Diego’s cAMPfield closed a $180M Series A to advance prifemilast, a once‑daily oral PDE4B inhibitor, into global trials for IBD.

Limoncello has opened in La Mesa Village, bringing Amalfi‑coast flavors, a glass‑enclosed pasta room and a $15.95 build‑your‑own pasta Tuesday special. The menu mixes seafood, braised meats and housemade pasta.

A state anti‑hate grant that funded 27 San Diego nonprofits is at risk as Sacramento budget talks leave renewal uncertain.

A county grand jury lauds recent protected lanes but warns San Diego’s bike network remains patchy, under‑maintained and unevenly distributed.

County Animal Services removed dozens of animals from a Rancho Santa Fe property after a report of possible horse neglect. Investigators say the animals are now in county care as the probe continues.

A judge denied a CEQA challenge, allowing All People’s Church to move forward with a 900‑seat sanctuary on a six‑acre Del Cerro parcel.

Biogen agreed to buy San Diego‑based RayThera for up to $1 billion, adding early‑stage immunology candidates and a lead program heading into Phase 1.

National City’s council unanimously named Douglas Schulze city manager and Heidi Skinner city attorney on Wednesday, a bid to end years of leadership churn. The hires come as the city wrestles with tight budgets.

A brush fire in Mission Valley closed eastbound Friars at Santo on Wednesday and snarled local traffic as crews worked the scene.