A germline‑targeting HIV vaccine produced broadly neutralizing antibodies in about 44% of vaccinated primates, researchers report. The Nature study is a proof‑of‑principle but not proof of protection.

Patchy fog this morning clears to mostly sunny; coastal highs around 77°F. Inland valleys and deserts face heat advisories and an extreme-heat warning through Thursday.

Scoopy Scoopy is opening its first permanent scoop shop in Leucadia, expanding from weekend pop‑ups to a 12‑flavor counter and pints to go. The soft open is set for July 8.

A metal bar fell from a truck and pierced a pregnant driver’s windshield on I‑15 near Temecula; CHP says the mother and her unborn twins are expected to be fine. Authorities released photos and urged drivers to secure loads.

Morning fog and mid‑70s at the coast; inland valleys and deserts face dangerous heat midweek.

National City approved a Comic‑Con–backed Meeting of Styles mural festival for July 19 that will turn I‑805 underpasses into public art with temporary road closures.

MAKE Cafe’s Normal Heights outpost pairs daytime farm-to-table service with a 12-week paid training program that aims to move immigrant and refugee women into long-term jobs.

Regulators say a Sorrento Valley clinic compounded and administered GLP‑1 injections without proper sterile controls; the Medical Board is seeking to revoke a doctor’s license.

Cool, cloudy mornings give way to sun and a high near 77°F today. Inland areas warm through the week with a minor to moderate heat risk.

Cool, cloudy coast for San Diego on Saturday, July 4, 2026, with inland highs near 75°F. Fireworks may create brief smoke and reduce visibility along the waterfront tonight.

The county assessor certified a record $845 billion assessment roll for 2026, adding about $39 billion while delivering $346 million in targeted tax relief. The total boosts local revenue even as sales slow.

A newly obtained FBI affidavit alleges three men who called themselves “skinheads” carried out racially motivated attacks near Oceanside Pier, injuring three people.

CBP officers at the San Ysidro crossing say they recovered more than 121 pounds of meth hidden inside a vehicle dashboard. Officials say the seizure joins a string of large interceptions at the port.