Sionna Therapeutics is laying off about 27 workers in Waltham after its cystic fibrosis drug flopped in trials.

Alyx says her car was rammed several times outside Yesterday's Bar and Grill after a dispute over an unpaid tab. Police want help identifying three suspects.

Two Kenner councilmembers want Louisiana's AG to check whether colleagues broke open meetings law picking an aviation board rep.

A Flood Watch covers Phoenix through Wednesday evening as thunderstorms bring heavy rain and flash-flood risks. Triple-digit heat returns by the weekend.

San Diego starts Wednesday with morning clouds before a sunny, mild afternoon. Seasonal temperatures continue into next week, with coastal temperatures in the 70s.

Portland's forecast calls for upper-70s to low-80s interior highs Wednesday, while low clouds and patchy fog are possible in interior valleys Tuesday morning. Thursday is expected to be the warmest day, while the Friday-through-weekend outlook remains uncertain but generally dry.

Officers will swap patrol cars for the stage as tickets go on sale for the 2nd Annual Rock with Cops at Joker's Comedy House.

The Dunwoody Village courtyard that grew from Bar{n} to five concepts marks five years with a costume party this October.

An anonymous donor's record gift will fund a five-year specialist to fight invasive honeysuckle choking French Park in Amberley Village.

Ascendco Health's new River North lab lets hospital staff test surgical instrument tracking before signing a contract.

A Volusia County father says a video appears to show his son attempting the dangerous Blackout Challenge.

The Waters Church expects roughly 1,000 men this Sunday for grilled ribeye, wings and a Gold Star memorial display.

JSO is investigating a fatal crash near a busy Love's Travel Stop in Baldwin, with a woman reported dead and no identity provided.