Five people in the St. Louis area were charged after prosecutors say they stole $511,000 from a state child‑care expansion grant program. The group faces federal counts including wire fraud and identity theft.

Mid‑America Transplant has begun flying donor blood samples along a new Missouri drone corridor, trimming delivery time and costs while testing a Rolla hub. Partners say the route could improve access for rural hospitals.

A 48-year-old Chicago man died early Wednesday after his semi ran off Route J at Audrain County Road 481. The crash closed Route J for hours while crews cleared the scene.

Two relatives face multiple felony charges after a March 2 shooting in Berkeley that ended when their car crashed into a house, prosecutors say.

Le Petit Chef’s projection-mapped dinner opened March 12 at Le Méridien St. Louis Clayton, pairing animated storytelling with multi-course menus from $49–$149.

A St. Louis police officer is in critical condition after a medical emergency during a training exercise, the department said. Officials offered few details.

Missouri’s Senate approved a bill to ban most intoxicating hemp products, aligning state law with a federal crackdown and reshaping where low‑dose THC items can be sold.

Spire closed a $2.48B deal to buy Piedmont's Tennessee gas unit, folding about 200,000 customers and nearly 3,800 miles of pipeline into Spire Tennessee.

State Sen. Angela Walton Mosley filed to run for St. Louis County executive, reviving scrutiny of a Sept. town‑hall scuffle with County Councilwoman Shalonda Webb.

One person was killed and another critically injured in an early‑morning Ferguson shooting. Police say the incident is not believed tied to a school‑area shooting the night before.

A condemned south St. Louis apartment complex left families scrambling after years of trash, pest complaints and a trash fire that destroyed a unit.

Workers who helped build One Foundry Way asked a judge to certify a class action alleging they were underpaid during construction on the Midtown project.

Via's on-demand vans now cover three St. Louis County zones for $2 trips, funded with roughly $6.34M. Some officials say the service fills gaps; others warn it's replacing buses.