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Gov. DeSantis Touts Success of Florida's SAFE Program in Orlando, Citing 2,100 Arrests and Major Fentanyl Seizures

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Published on September 02, 2025
Gov. DeSantis Touts Success of Florida's SAFE Program in Orlando, Citing 2,100 Arrests and Major Fentanyl SeizuresSource: State of Florida, Public domain, via Wikimedia Commons

Florida Governor Ron DeSantis emphasized the strong results of the State Assistance for Fentanyl Eradication (SAFE) program at a news conference in Orlando. The SAFE initiative, designed to bolster the fight against fentanyl throughout the state, has reportedly led to the arrest of 2,100 individuals and the confiscation of significant amounts of illicit substances, reported WESH.

In a detailed overview, DeSantis underscored the program's impact, noting the seizure of 485 pounds of fentanyl, enough, he says, to "kill one-third of the population of the United States", and nearly 63,000 fentanyl pills. DeSantis also highlighted the successful capture of a high-profile cartel member in Orlando, along with other seizures, which included over half a million dollars in drug cash, several firearms, and vehicles used in drug trafficking operations. Meanwhile, Lt. Gov. Jay Collins and Seminole County Sheriff Dennis Lemma lent their support at the event, details of which were shared by FOX 35 Orlando.

The SAFE program was established in 2023 with a $15 million initial allocation and continues to be funded, set to receive $8.5 million for the 2025–2026 fiscal year. DeSantis credited various law enforcement agencies for their collaboration in this initiative, including significant efforts by the Orange County Sheriff's Office and Polk County Sheriff's Office, which led to substantial seizures of fentanyl linked to Mexican cartels. "FDLE, alongside our sheriffs and police chiefs, are making Florida the least hospitable state in America for cartel activity," Florida Department of Law Enforcement Commissioner Mark Glass stated, as per a FOX 35 Orlando report.

Detailing the wider implications of the SAFE program for community safety, DeSantis said, "These results are significant. These results have made our communities safer, these results have saved the lives of many Floridians." As the state continues to grapple with the opioid crisis, the governor plans to recommend additional funding for the program to sustain and enhance its effectiveness. In tandem with these efforts, State Attorney Monique Worrell is set to discuss the prosecution of fentanyl cases later today, further highlighting the state's multifaceted approach to combating the fentanyl epidemic in Central Florida.