Portofino’s Italian Restaurant is doubling down on Greenville, lining up a second location in the Augusta Road and Conestee area. The family-owned spot plans to move into 15 Conestee Avenue, the space most recently home to The Pharmacy at Augusta, and is shooting to start serving in early September. The news, shared on social media this week, adds fresh drama to an already busy Augusta Road dining strip.
As reported by WYFF, the update came from Facebook posts saying The Pharmacy at Augusta will close to make room for Portofino’s. WYFF noted that its story, published July 28, 2026, was pulled directly from social media rather than from a formal press release.
Portofino’s Haywood-Area Roots
Portofino’s currently runs its flagship in the Haywood Road shopping area. Business listings place the restaurant at 30 Orchard Park Drive in Haywood Plaza, according to YellowPages. The restaurant shares its menu and ordering details on its official website, Portofino's, where it describes itself as a family-owned Italian restaurant known for classic pastas and catering services.
The Pharmacy At Augusta Space
The Pharmacy at Augusta is listed at 15 Conestee Avenue on reservation platforms and features a brunch-to-dinner lineup on its profile on OpenTable. The Conestee property has seen a few changes in short order. Owners closed a Tipsy Taco at that address in 2025 before launching The Pharmacy at Augusta, a conversion first reported by FOX Carolina.
What Comes Next
The planned Portofino’s opening is the latest sign of both churn and growth along the Augusta Road and Conestee corridor, a stretch that hosts neighborhood festivals and a steady rotation of restaurant concepts, according to local listings on Greenville.com. With an early September target date reported by WYFF, Portofino’s will have a relatively short runway to transform the former Pharmacy space and get service underway.
