The Pro Football Hall of Famer helped carry St. Louis to a Super Bowl title in 1999. His diagnosis comes amid growing scrutiny of football and neurological disease.

The beloved St. Louis sandwich shop is taking over a former Goodcents storefront on Vogel Road in Jefferson County.

The Alzheimer's blood-test maker will anchor WashU's Catalyst building as it plans to triple its hometown operations.

TerraWatt wants to turn the idled Alton Steel site into the Riverbend Technology Center, with no tax breaks requested. An open house is set for next Tuesday.

Beyond Housing's new Page Avenue project is planned as a 42-unit mixed-income development with two- and three-bedroom apartments.

PFC John Robert Stovall vanished in Korea in 1950. Flagman's Mission Continues seeks volunteers to line his funeral route with 600 flags next week.

Blackburn Park hosts a free smash-and-compost event Nov. 7, with Brentwood volunteers pitching in to divert jack-o-lanterns from the trash.

Willie and Taiya Herndon face charges in the I-170 shooting that killed McCluer North senior Alyssa Wilson, who planned to join the Army.

Art of PAWS & People returns next Saturday at the Gatsby Ballroom STL, with 50 people still waiting for pet care help.

The Kawasaki Ninja 400 rider was ejected and killed on northbound I-55 in Jefferson County. His identity has not been released.

A paramedic supervisor rescued a resident tangled in a ladder at a second-floor window during a Castleman Avenue fire.

Matthew Higgins hid in the woods before surrendering to deputies at the Deana Drive scene, officials say.

Christopher Hall and Bryant Pirtle face up to life after pleading guilty to Devon Williams's murder near I-70.