BioSTL is facing a funding squeeze in its 25th year as institutional donors pull back while early‑stage deal flow in St. Louis surges. The nonprofit is seeking new donors and structures to keep startups moving.

A 16‑story, 190‑room Hampton Inn at 333 Washington Ave. has been listed for sale; brokers say a buyer could reposition the property near the Gateway Arch.

An analysis of phenology data shows St. Louis’ first leaves now arrive about seven days earlier than in the early 1980s, a shift that affects allergies, pests and crop risk. Local extension and phenology tools can help residents and growers adapt.

A University City councilman has mounted a mayoral challenge, arguing development hasn’t translated into timely repairs and neighborhood investment.

An adult pedestrian was fatally struck on eastbound I‑70 at Union Boulevard early Friday, closing eastbound lanes while investigators processed the scene.

Webster Groves approved a roughly $225,000 severance for City Manager Dr. Marie Peoples as she departs April 3, the city says the payout covers pay, retirement deferrals and a two-month consulting window.

A late‑night stabbing near Village Square left an adult and a child hurt; a suspect was arrested nearby and Hazelwood police have launched an investigation.

Masyn Winn hit a walkoff single Wednesday and was later involved in a single‑car crash on I‑64; the Cardinals say he was evaluated and has no serious injuries.

Grandview R‑2 put a four‑day school‑week reauthorization on the ballot for next Tuesday as Missouri grapples with falling teacher retention; researchers say the schedule helps hiring but brings trade‑offs.

Le Petit Chef’s projection-mapped dinner opened March 12 at Le Méridien St. Louis Clayton, pairing animated storytelling with multi-course menus from $49–$149.

State Sen. Angela Walton Mosley filed to run for St. Louis County executive, reviving scrutiny of a Sept. town‑hall scuffle with County Councilwoman Shalonda Webb.

Workers who helped build One Foundry Way asked a judge to certify a class action alleging they were underpaid during construction on the Midtown project.

A motorcyclist was killed Tuesday evening on Highway 94 near Klondike Park outside Augusta. Police say the motorcycle left the roadway and the crash is under investigation.