Chicago’s Letter AI landed a $40M Series B led by Battery Ventures and launched Letter Compass to bring AI coaching into live deals. The company says it will triple hiring this year.

Amazon will launch Prime Air drones from Markham and Matteson to deliver small orders within an eight‑mile radius. Community demos and a March 2 meeting are planned.

Neil Bluhm has pledged $50 million to Northwestern Medicine to expand cardiac research, recruit doctors and boost inpatient capacity as the system plans a new Streeterville tower.

A Cook County judge certified a BIPA class against Apple over Siri voiceprints, potentially including millions of Illinois users and raising high-dollar privacy questions.

Researchers found airline and hotel loyalty accounts being traded on dark‑web forums, sometimes for pennies. Experts urge unique passwords, MFA and close account checks.

ActiveCampaign bought Feedback Intelligence to speed improvements to its Active Intelligence AI. Founder Chinar Movsisyan will join the Chicago firm's product team.

Adtalem — the largest U.S. health-care educator — announced a corporate rebrand to Covista and a new push into research, training and philanthropy to help ease staffing shortages.

Northwestern announced nearly $25M from trustee Kimberly Querrey to launch the Simpson Querrey Brain Health Institute, aiming to measure and prevent cognitive decline.

Rush University is testing Apple Vision Pro headsets paired with AI during colonoscopies in a usability trial that could inform an FDA submission and wider hospital use.

Northwestern and Lurie Children’s unveiled a hair‑thin probe that measures fetal heart rate, oxygen and temperature during in‑utero surgery.

Chicago startups raised about $2.6 billion in 2025 as national VC totals surged on AI megadeals, leaving local backers worried that the Midwest is being bypassed.

AbbVie paid $650M up front to license RemeGen's RC148 outside China; the deal and a Tempe plant purchase underscore a fresh push into oncology and U.S. manufacturing.

The Chicago Tribune joined other newsrooms in asking a Manhattan judge to sanction OpenAI, alleging the company deleted and substituted millions of ChatGPT logs.