Sunny, cool Saturday with a high near 52°F. A warmup Sunday–Tuesday, storms and gusty winds likely late Tuesday night into Wednesday.

A NEJM‑published LATITUDE trial shows monthly cabotegravir‑rilpivirine injections reduced regimen failures among people who struggle with daily oral HIV therapy. University of Cincinnati clinicians were among the lead sites.

A grand jury indicted 51-year-old Wade Hensgen after a Nov. 16 overdose in Clermont County, deputies say he faces involuntary manslaughter and trafficking counts and tips are requested.

A pre-dawn generator fire at Duke Energy’s Woodsdale station challenged crews because the unit remained energized at roughly 345,000 volts. Crews extinguished the blaze after power was shut off, no injuries were reported.

Police cleared The Banks after Opening Day, shutting down the riverfront and arresting several people as officers dispersed the crowd.

Light rain and gusty north winds will slow Friday's commute in Cincinnati. Cooler tonight, sunny Saturday and an active, warmer week ahead.

A Children’s Defense Fund‑Ohio report finds firearms are now the leading cause of death for Ohio children and teens, exposing racial gaps and urging prevention policies.

Xavier University announced a $2 million gift as it builds the nation’s first Jesuit osteopathic medical school, adding momentum to a $500M fundraising campaign.

A Middletown man was seriously injured when a police cruiser struck him on Grand Avenue, police say. He slid about 50 feet and was taken to Atrium Medical Center.

Cincinnati has named 12 volunteer members to what leaders call Ohio’s first LGBTQIA+ advisory commission. The panel will advise City Council on safety, services and policy.

Federal prosecutors say a Dayton man fired about a dozen rounds at officers during a standoff and later arranged a peaceful surrender. The Southern District of Ohio complaint lists multiple federal weapons and assault counts.

The Ohio House approved HB217 to require law enforcement to enter missing‑person reports into the federal NamUs database within 30 days, the bill now heads to the Senate. Advocates say it closes a long‑standing reporting gap.

A new Ohio bill would bar nonresidents who lack lawful presence from driving in the state and make violations a first‑degree misdemeanor, with citations forwarded to ICE. The measure also directs the attorney general to sue other states in specific crash cases.