Morning fog and mid‑70s at the coast; inland valleys and deserts face dangerous heat midweek.

Vertex will buy Crinetics for about $10 billion, adding an FDA‑approved oral acromegaly drug and a late‑stage CAH candidate. The deal is expected to close in Q3 2026.

National City approved a Comic‑Con–backed Meeting of Styles mural festival for July 19 that will turn I‑805 underpasses into public art with temporary road closures.

More than 100 pets arrived at local shelters after July 4 fireworks. The San Diego Humane Society is waiving reclaim fees and updating its lost-and-found listings to speed reunifications.

MAKE Cafe’s Normal Heights outpost pairs daytime farm-to-table service with a 12-week paid training program that aims to move immigrant and refugee women into long-term jobs.

FAA staffing limits and summer storms produced delays and a few cancellations at San Diego International during the busy July 4 travel window.

A woman was run over while lying in a Jamacha/Lomita shopping center parking lot Sunday and suffered multiple fractures. Police say an investigation at 920 Cardiff St. is underway.

Regulators say a Sorrento Valley clinic compounded and administered GLP‑1 injections without proper sterile controls; the Medical Board is seeking to revoke a doctor’s license.

An 85‑year‑old Encinitas woman was found unresponsive with injuries investigators deem suspicious; the county's homicide unit has taken over the probe.

San Diego pump prices slipped to $5.42, marking the 44th decline in 45 days as national averages ease on lower crude. Relief is steady but local costs remain high.

The National Weather Service warns San Diego’s desert communities will face life‑threatening heat July 7–9, with highs near 117°F and county cooling options available.

A 36-year-old pedestrian was struck and killed early Sunday on Clairemont Mesa Boulevard in Kearny Mesa. Police say the driver stopped and investigators do not suspect impairment.

A vacant two‑story office building in Serra Mesa caught fire just after midnight, drawing a third‑alarm response. Firefighters prevented spread and no injuries were reported; investigators are probing the cause.