A suspect was arrested Wednesday after threats targeted the City of St. Charles School District's graduation; police and prosecutors are investigating.

Sunny, mild Thursday turns stormy overnight; heavy rain possible during the Friday morning commute.

An early WashU‑led trial found a personalized DNA vaccine was safe and triggered strong immune responses in glioblastoma patients, with one participant still cancer‑free nearly five years.

South Carolina raids targeted The Abduction Dispensary this week; owner Jesse Turner of Union, Missouri is facing trafficking charges.

A multimillion-dollar lawsuit over a 2013 minority stake sale in Lion's Choice is headed to trial, with plaintiffs alleging a trustee engineered a restructuring to enrich himself.

A 20-year-old motorcyclist died early Thursday after his bike left eastbound I‑64 and struck a guardrail near the I‑270 interchange, authorities said.

A man was found shot in the 4300 block of South Broadway and later died at a hospital. Homicide detectives are investigating.

Security video shows two women repeatedly taking donated clothing from a St. Peters church's drop box, church leaders say.

TraffickCam, built in St. Louis, pairs traveler-uploaded hotel photos with AI to help NCMEC and police identify locations — and has been linked to at least one rescue.

Firefighters recovered a body from the Mississippi River near S. Broadway and E. Soper Street in Carondelet; officials say details remain limited.

A St. Louis widow has sued for siren logs and tree‑inspection records after the May 16 tornado that killed her husband. She says months of requests were ignored.

A St. Charles woman pleaded guilty in federal court after court filings said she hired an undocumented dishwasher at Golden Apple Buffet who worked 12‑hour shifts six days a week.

O'Fallon police warn of spoofed "missed jury duty" calls that push victims to Bitcoin ATMs. The department says hang up and report suspicious calls to local authorities.