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High‑Glyphosate Midwest Counties Show Rising Late‑Stage Lymphoma Rates

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Published on March 20, 2026
High‑Glyphosate Midwest Counties Show Rising Late‑Stage Lymphoma RatesSource: Unsplash/Anirudh

In a new look at who sprays what and who gets sick, counties that use the most glyphosate, the active ingredient in Roundup, are reporting higher rates of late-stage non-Hodgkin lymphoma. The sharpest clusters show up in the Upper Midwest, where heavy row-crop spraying overlaps with pockets of more advanced cancer diagnoses.

What The Data Show

Food & Water Watch mapped counties in the top 20 percent for glyphosate application and compared that list with county-level non-Hodgkin lymphoma incidence. The group reported that 60 percent of these high-spray counties have NHL incidence above the national average, and that share rises to 71 percent when the analysis is limited to late-stage diagnoses. Roughly 30 percent of the highest-spray counties qualify as NHL “hot spots.” These findings are from Food & Water Watch.

Investigative Reporting Fills In Local Detail

Investigate Midwest, which has been publishing county-level overlays and analysis, found that 60 percent of the top 500 pesticide-use counties had overall cancer rates above the national average, then paired that work with the Food & Water Watch focus on late-stage disease. Amanda Starbuck, a researcher with Food & Water Watch, told Investigate Midwest that “a lot of the strongest cases that can make it into litigation are the more aggressive, late-stage (cases),” which helps explain why mapping late-stage diagnoses matters so much to plaintiffs and their lawyers.

Legal And Policy Fallout

The reporting lands in the middle of major legal moves. Bayer and plaintiffs announced a proposed 7.25 billion nationwide class settlement in February as part of an effort to resolve years of Roundup litigation, as reported by The Associated Press. Advocates say the new mapping is also timely because pesticide makers are pushing state and federal protections that would limit lawsuits. Food & Water Watch calls those proposals “Cancer Gag Acts” and has flagged federal and state bills that would curb liability for manufacturers in certain cases, a point raised in the group’s brief and data brief.

What Scientists And Statisticians Say

Experts stress that a county-level overlap is a signal, not proof of causation, and regulatory panels and large cohort studies have come to differing conclusions. The World Health Organization’s cancer agency, IARC, classified glyphosate as “probably carcinogenic to humans” in 2015. A major prospective analysis from the Agricultural Health Study, published in the Journal of the National Cancer Institute, did not find an overall association between glyphosate and lymphoid cancers.

Investigative groups note that their maps draw on U.S. Geological Survey pesticide estimates and NCI State Cancer Profile data. They also warn that suppressed small-county counts, different exposure pathways, and other local risk factors such as radon, nitrates, and occupational exposures make simple cause-and-effect claims risky. The maps, they argue, are best read as a set of places that need deeper, local exposure and health studies, not as the final word on what is making people sick.