St. Louis/ Crime & Emergencies

Three Seriously Injured in Highway 50 Crash Near Centertown

AI Assisted Icon
Published on November 11, 2026
Three Seriously Injured in Highway 50 Crash Near CentertownSource: Google Street View

Three people were seriously injured Tuesday afternoon when two vehicles collided on U.S. 50 at Lookout Trail in Cole County, near Centertown.

A southbound 2015 Toyota Tacoma was trying to cross the westbound lanes around 4:15 p.m. when a westbound 2022 Nissan Altima struck it on the side, KRCG reported. A Missouri State Highway Patrol crash report cited by ABC 17 describes the pickup being hit on its left side; the front of the Toyota then struck a road sign.

The Tacoma's driver, a 68-year-old man from Mokane, was seriously hurt and taken by private vehicle to Capital Region Medical Center. The Altima's driver, a 24-year-old woman from California, Missouri, and her passenger, a 48-year-old woman from the same town, were also seriously injured. Cole County ambulance took both women to University Hospital in Columbia.

All three were wearing seat belts. Both vehicles were totaled, and the crash delayed traffic on Highway 50 for part of the afternoon.