A Pittsburgh mother says detectives still haven’t answered who killed her son, Stanley Howe Jr., nearly 10 months after the Wiltsie Street shooting.

City Council opened the process Tuesday to pay $445,000 in settlements to 10 people injured when the Fern Hollow Bridge collapsed in January 2022.

Pitt researchers turned a harmless eye bacterium into a prototype "living eye drop" that secretes anti-inflammatory IL-10 and sped cornea healing in mice. The proof-of-concept could reduce repeated dosing, but human trials are still distant.

A man was shot Monday in Pittsburgh’s Homewood North and taken to the hospital in critical condition. Frankstown Avenue was closed as detectives processed the scene and searched for witnesses.

A teenage boy was critically injured in a shooting Sunday on James Street in Turtle Creek as Allegheny County Police investigate. Tips are being sought.

A crash on Route 66 at Mamont Drive left one person dead and another seriously injured; authorities say the cause is under investigation.

Pennsylvania State Police say fresh leads have emerged in the 1973 New Castle homicide of Frank DeWayne Iwanejko. Investigators are offering a $5,000 reward and asking anyone with information to call 724-598-2211.

A Tarentum pig rescue took in roughly 80 pigs after police seized dozens from a condemned Rostraver home. Volunteers built pens while the nonprofit faces major medical and fundraising needs.

A second man has been arrested in the September drowning death of Stephen Williams. Police say surveillance video helped investigators identify suspects and led to new homicide charges.

A 64-year-old Westmoreland County man was arrested after traveling to Areford Community Park to meet who he thought was a 13-year-old, police say.

El Colibri opened a Garfield storefront at 5331 Penn Ave., bringing birria tacos, huaraches and vegan twists off the market and into a Penn Avenue storefront.

A century‑old downtown hotel in the Fulton Building will relaunch this summer as The Atterbury after a multi‑million‑dollar renovation that refreshed 300 rooms and the rotunda.

Italian microreactor maker Terra Innovatum has opened a U.S. headquarters in Pittsburgh as it advances licensing and a planned FOAK deployment for its SOLO reactor.