UC San Diego researchers developed a vaccine targeting an enzyme variant related to acne, potentially offering a more targeted treatment without harming beneficial skin bacteria.

Trader Joe's is set to open a new store in Santee, exciting local shoppers who have been traveling to nearby cities for their popular and unique groceries.

Chula Vista Police officers rescued a man from a burning car on Interstate 5 after using a drone to pinpoint the vehicle's location. The man later expressed gratitude, having survived thanks to the officers' quick actions.

San Diego Zoo debuts the once-thought-extinct Lord Howe Island stick insect, a significant event for conservationists and exhibiting the zoo's involvement in the species' preservation efforts.

A pedestrian died on I-5 after being hit by multiple cars, causing lane closures and traffic delays, with no driver injuries reported. The pedestrian's actions and driver sobriety are under investigation.

San Diego police have arrested three teens suspected of committing a series of armed robberies in the area, recovering firearms including a ghost gun.

The SDPD released bodycam footage showing a deadly shooting involving a suspect and a police sergeant in 4S Ranch. The sergeant was injured and the suspect killed during the exchange.

The Lemon Avenue Parking lot in La Mesa is closing for renovations from January 2 to February 29, 2024, with alternative parking spaces suggested on nearby streets.

The FBI offers a $10,000 reward for information on missing 13-year-old Raine Gonzales from Brawley, California; details about her last sighting with Lorenzo Guerrero are shared.

Escondido police conducted a DUI checkpoint, resulting in three arrests for DUI, an outstanding warrant, and drug possession out of 1,496 screened vehicles. The location was chosen based on crash data and is part of efforts to enhance road safety.

The Via Vera Cruz in San Marcos is reopening on December 18, with a bridge dedicated to former Councilmember Pia Harris-Ebert celebrated by city officials.

Deputies arrested a man linked to e-bike thefts in Lemon Grove, finding drugs, ammo, and firearms at his residence, and arrested three associates on various charges.

A fire in University City, San Diego, battled by multiple firefighting crews, resulted in no injuries but displaced five adults, now assisted by the Red Cross.