A new DOB filing shows plans to replace the former McDonald’s at Broadway and Thomas with a 21‑story tower that could bring about 50 apartments to Tribeca.

A roughly $20M offer aims to buy Manhattan Country School’s Upper West Side campus, potentially deciding whether the building stays in education.

The FDA cleared Enhertu for neoadjuvant and adjuvant treatment of HER2‑positive early breast cancer after DESTINY trials showed higher pCR and lower recurrence risk.

A 2-alarm blaze at 1086 Myrtle Ave in Bushwick injured one firefighter and left several tenants displaced after crews spent about 90 minutes bringing flames under control.

A 40-year-old man was slashed and stabbed in front of a Flatbush strip mall. NYPD Crime Stoppers posted a wanted bulletin and is seeking tips.

TSQ LIVE returns to Times Square with free concerts, DJ sets, dance classes and family programming across the Broadway plazas through September.

Katz’s has reopened the Ludlow Room — a restored 68-seat dining room closed since 1949 — and will use it for extra seating and private events on the Lower East Side.

Naftali Group and Access Real Estate closed a $374M refinance on Phase I of Williamsburg Wharf. Barings replaces Bank OZK and leasing at the rental buildings is running hot.

Montreal's Cozey has leased 10,146 sq ft at 160 Fifth Ave for a Flatiron flagship under a 10-year deal.

Mayor Mamdani and DOT will widen Sixth Avenue’s protected bike lane to 10 feet between W14 and W31 and add new pedestrian space through Herald Square ahead of the World Cup.

A 22-year-old man was shot in both legs overnight on Miller Avenue in East New York. Police say the case is developing.

The mortgage on Coach’s Fifth Avenue flagship was moved to special servicing amid default fears, putting pressure on one of Midtown’s highest-profile retail corners. Lenders and owners now face fast-moving decisions.

Russia accused Latvia at the U.N. of allowing Ukrainian drone launches; Latvia and the U.S. rejected the claim as NATO intercepted a suspected drone over Estonia.