An 11‑story life‑sciences tower at 3201 Cuthbert opened Wednesday, consolidating Drexel research into University City and bringing new lab tenants and commercial space.

A new 5K in Fairmount Park will kick off Philadelphia’s 250th celebrations this Memorial Day weekend.

A 31-year-old man was arrested and charged after a Dec. 27 head-on collision on Aramingo Avenue in Port Richmond that left a 45-year-old driver dead.

Cabelle St. John is stepping down as Sen. John Fetterman's chief of staff, the latest senior exit as the office grapples with turnover and scrutiny.

Eagles pass rusher Nolan Smith Jr. was arrested in Twiggs County, Ga., on suspicion of speeding and reckless driving. The arrest comes weeks after the team picked up his fifth-year option.

A scrapyard fire near 12th and Glenwood in North Philadelphia sent smoke over the tracks and halted rail service. Crews worked to secure the scene as agencies paused trains.

After 42 years leading Mural Arts, Jane Golden will step down in July 2026 but will remain to finish major semiquincentennial projects. Her exit starts a national search for a successor.

Two older Lehigh County residents died at home Monday as an early heat wave pushed heat indexes near 100 degrees. The coroner ruled the deaths accidental and urged neighbors to check on vulnerable people.

Adam's Way, an inclusive mixed-use project in Doylestown, unveiled concept plans and confirmed land acquisition. Organizers have secured property but still face a roughly $5M private fundraising gap.

Bar Caviar, a Champagne-and-caviar lounge from Ken and Vittoria Schutz, is coming to the DWIGHT D Hotel near Rittenhouse with about 50 Champagne selections and five caviars. No official opening date has been announced.

Philadelphia health officials say patients who visited Smiles at Rittenhouse Square between April 2025 and May 2026 should be tested for HIV and hepatitis; a hotline is available.

Two Warrington Township parents were charged after police say a "guest list only" Halloween party at their home drew roughly 150 teenagers.

Amazon Now brings groceries and essentials to Philadelphia doorsteps in about 30 minutes, with Prime fees starting at $3.99 and small‑order surcharges under $15.