Mark Cuban will headline an invite-only AI pitch at Carnegie Mellon on April 22 as Pittsburgh courts startups with a multi-million-dollar prize and recruitment push.

Thirty venture firms have soft‑committed about $240M to a new CMU program pairing researchers with investors and six months of mentorship. The push aims to move lab projects into investable deep‑tech startups.

UPMC Children’s is nearly ready to open a 50,000‑sq‑ft Heart Institute in Lawrenceville, bringing cath‑MRI suites and the region’s first pediatric cardiac rehab gym.

UPMC Hillman is rolling out PET‑guided radiotherapy, surface‑guided systems and radiopharmaceuticals across its network — clinicians report faster relief and fewer side effects for some patients.

Skild AI will integrate its Skild Brain into Nvidia Blackwell production lines via Foxconn, tying a Pittsburgh startup to the global AI hardware supply chain.

Dr. Andre Samuel visited South Fayette High to recount his path from early setbacks to a Ph.D. and to preview the Citizen Science Lab’s Hill District plans. The nonprofit is turning the MLK site into a community STEM hub.

A tiny retinal chip and smart glasses helped a Pittsburgh trial participant begin to see forms again. An international study published last year reported meaningful improvement for most wearers.

Pittsburgh startup Efficient Computer landed $60M to speed development of its ultra-efficient Electron E1 processor and expand its engineering team.

Pitt researchers identified hypothalamic enzymes FAK and PYK2 that restored leptin response in mice, producing major fat loss while preserving muscle — a potential new drug target.

The Carnegie Science Center in Pittsburgh, renamed the Kamin Science Center, is undergoing updates and will temporarily close for refinements, reopening with a free event on September 13.

Pittsburgh's Department of Finance partners with VRIDIAN to launch VIVA, a digital map for public interaction with the Treasurer's Sale property auction.

Gov. Josh Shapiro proposed a $50 million budget to boost Pennsylvania's life sciences sector, aiming to create jobs and foster innovation in the face of declining federal research funding.

Serbian Crown Princess Katherine underwent pancreatic cancer surgery at UPMC, remaining optimistic and resolved to continue her humanitarian work despite her health challenge. The royal family thanked her medical team and supporters.