CBP officers stopped more than 35 pounds of fentanyl pills at the Calexico Port of Entry. Officials have not yet released suspect or smuggling details.

A San Diego startup’s tiny autonomous boat recorded a Chinese guided-missile destroyer near the Philippines. The footage highlights the rising role of robotic maritime surveillance.

Mariachi USA returns to San Diego’s Rady Shell on September 26 with a stacked lineup, folklórico ballet and fireworks over the bay.

San Diego’s $205 million VA spinal cord injury center is finally complete after years of delays. Patients are expected to arrive in early 2027.

Breakfast Republic will close its North Park, Ocean Beach and Encinitas restaurants next Sunday as Rise & Shine shifts expansion elsewhere.

County investigators link 13 Salmonella cases to Ramona Family Naturals; mayo made with raw eggs is suspected.

A San Diego biotech is moving an investigational gout drug through late-stage trials, backed by $130 million in new financing.

Two separate rescues unfolded Tuesday at San Diego’s Sunset Cliffs, including one involving a fall into the ocean and another requiring a crane and stretcher.

San Ysidro’s community activity center reopened Tuesday after a $5.8M makeover, adding a new sports court, accessible playground and improved restrooms.

Clouds clear Wednesday in San Diego, but heat and dangerous surf are set to build into the weekend.

A state seed bank and a working draft strategy show California lacks the seeds, nursery capacity and funding to meet post‑fire replanting goals.

Mon Cheri Cafe & Bistro brings French pastries, crêpes and an all-day bistro menu to Encinitas' Coast Highway. The new spot serves breakfast through dinner and takes reservations.

A 30-year-old man was arrested after an attempted carjacking at the Massachusetts Avenue trolley station in Lemon Grove; deputies say the passenger was uninjured.