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Published on August 20, 2024
Eli Lilly's Game-Changer Tirzepatide Slashes Diabetes Risk by 94% for Pre-Diabetics with ObesitySource: Wikipedia/Momoneymoproblemz, CC BY-SA 4.0, via Wikimedia Commons

Eli Lilly and Company has reported that its drug, Tirzepatide, demonstrated a remarkable 94% reduction in the risk of adults with pre-diabetes and obesity progressing to type 2 diabetes when compared to a placebo. The drug, marketed as Zepbound for weight loss and Mounjaro for diabetes control, showcased its efficacy in a three-year study that has potential implications for those grappling with these health challenges. According to the Fox59 report, the study followed adults receiving weekly injections at differing dosages, with those on the highest 15 mg dose experiencing consistent weight reduction.

The CNBC covered the drug's continued weight loss benefits. This has important effects on public health and healthcare systems. The drug lowers the risk of type 2 diabetes and helps with weight management.

With obesity recognized as a chronic disease affecting an estimated 900 million adults worldwide, treatments like Tirzepatide could present a transformative option for individuals at increased risk of subsequent health issues. "Obesity is a chronic disease that puts nearly 900 million adults worldwide at an increased risk of other complications such as type 2 diabetes," said Jeff Emmick, M.D., Ph.D., vice president of product development at Lilly, in a statement captured by PR Newswire. "Tirzepatide reduced the risk of developing type 2 diabetes by 94% and resulted in sustained weight loss over the three-year treatment period."

In the study, 1,032 adults with pre-diabetes and obesity were monitored over a 176-week treatment period, followed by a 17-week off-treatment phase. The findings, which have been previously noted in primary analysis at 72 weeks in the New England Journal of Medicine, reinforce long-term therapy's potential benefits.