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Early Menopause Linked to 40% Higher Risk of Heart Attacks

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Published on March 19, 2026
Early Menopause Linked to 40% Higher Risk of Heart AttacksSource: Unsplash/Ali Hajiluyi

Early menopause is not just a footnote in your medical history, Chicago experts say. Local researchers report that women who stop having periods unusually early may face roughly a 40 percent higher lifetime chance of coronary heart disease, and that has cardiologists across the city pushing for tougher questions and closer screening during routine midlife visits.

Study Finds Bigger Lifetime Risk After Premature Menopause

To get those numbers, researchers pulled together individual-level data from several long-running U.S. cohort studies and tracked what happened to women over time. They focused on premature menopause, defined as menopause before age 40, and compared those women with peers who did not enter menopause that early.

The analysis, published in JAMA Cardiology, found that premature menopause was tied to about a 40 percent higher lifetime risk of developing coronary heart disease, even after the usual suspects such as blood pressure, cholesterol, and smoking were taken into account.

Clinicians Want Menopause Age On Medical Charts

In light of those findings, local researchers and clinicians say that a simple question about menopause timing should be as standard as asking about smoking or family history. As reported by CBS News Chicago, the Northwestern team argues that putting age at menopause in the chart could help flag women who need closer follow-up. An American Heart Association summary of the work echoed that point, recommending earlier and more tailored prevention for those with premature menopause.

Guidelines: Treat Premature Menopause As A Risk Enhancer

National guidance is already inching in that direction. The ACC/AHA primary prevention guideline lists premature menopause, again defined as before age 40, as a "risk-enhancing" factor that should be weighed when clinicians discuss prevention with patients.

The JAMA Cardiology analysis backs that up, showing that premature menopause is a red flag for higher lifetime risk. At the same time, plugging menopause age into standard 10-year risk calculators did not significantly sharpen short-term predictions. Experts say that finding is a cue for long-haul vigilance and individualized counseling, not an automatic green light for new medications, in line with the ACC/AHA guideline.

What Chicago Women Should Know

Heart disease remains the number one killer of women in the United States, which makes the midlife years a crucial window to get ahead of trouble, according to the Centers for Disease Control and Prevention. Local specialists say that for Chicago women, that should include mentioning when menopause started, not just how it felt.

Patient guidance from Northwestern Medicine encourages women to tell their clinicians the age at which their periods stopped, so blood-pressure checks, cholesterol testing, and other preventive steps can be bumped higher on the priority list when needed.

Experts stress that early menopause is a warning sign, not a do-it-yourself treatment plan. Choices such as menopausal hormone therapy carry benefits and risks that depend on age and overall health, so any decision should be made case by case and guided by current clinical advice from expert centers like the Mayo Clinic. If your periods stopped well before 40, write down the age of your final period and bring it to your next primary-care or cardiology visit, so your care team can factor it into long-term monitoring and prevention.

Chicago-Science, Tech & Medicine