A Fishers teen survived a catastrophic e-bike crash; doctors and national data show a sharp rise in e-bike head injuries and experts urge helmet use and clearer rules.

Eli Lilly is adding $4.5 billion to its Lebanon manufacturing buildout and opened its first genetic‑medicine plant, raising Indiana commitments above $21 billion.

Division I is advancing a "five‑in‑five" eligibility plan that would lock careers into five seasons across five years. Coaches like the certainty but warn it could erase redshirts and invite legal fights.

A federal judge refused to dismiss St. Philip Neri’s suit over the Holy Cross landmark designation, keeping the preservation fight alive and the case moving forward.

A woman died after her SUV struck a tree on Guion Road Tuesday. Authorities say investigators are working to determine what happened.

A judge has issued a warrant for Damarthson Daniel after investigators tied his vehicle to the Dec. 26 hit-and-run that left Tanya Ethridge dead. Police say surveillance and phone records helped identify the car.

A late-night shooting on Indianapolis' east side left one person dead; IMPD says the incident was isolated and no suspect was in custody.

A late-night shooting at a Conoco near 10th and Emerson left one man dead and another in critical condition. IMPD says the scenes are linked and detectives are asking for tips.

City inspectors ordered four buildings at Williamsburg Way vacated after finding flooding, electrical hazards and other safety risks. The units will remain closed until repairs pass inspection.

A basement fire in Carmel's Arts & Design district drew multiple fire and EMS units Tuesday; crews had it under control by about 5:30 p.m. and damage assessments are underway.

Gray Brothers Cafeteria is auctioning hundreds of kitchen and dining items after closing its Mooresville dining room; inspections next Thursday and bidding closes next Friday.

A Chicago physician faces felony counts after investigators say he administered IV NAD treatments from a Warsaw home; syringes and vials were found in his car.

A JEAN Team search in Marion recovered suspected meth and fentanyl, a firearm and led to several arrests and preliminary charges.