A suspected DUI driver led deputies on a high-speed chase, ending in a crash involving multiple vehicles and minor injuries, resulting in his arrest for DUI and related charges.

A sexually violent predator, Alan Earl James, may be released to Campo as San Diego Court orders his conditional release and proposes his placement at a local address, with a hearing set for community input.

Breeze Airways introduces five new nonstop routes from San Diego International Airport, starting as low as $59 one-way, with a promotional discount available until January 12.

A fire on the 4th floor of a high-rise on 14th Street prompted evacuations and a third-alarm call. Sprinklers extinguished the flames, resulting in no fatalities but $150,000 in damages. An accidental lithium-ion battery fire is cited as the cause.

Johnson & Johnson is set to acquire Ambrx Biopharma for $2 billion to enhance its cancer treatment portfolio, particularly in advanced antibody drug conjugates.

San Diego Zoo Wildlife Alliance collaborates with Illumina to sequence the DNA of North American koalas, focusing on combating diseases such as Koala Retrovirus (KoRV).

A tragic accident on State Route 94 claimed the life of a young motorcycle rider, Jadahn Schaefer, 27, of Lemon Grove...

A National City man was sentenced to nearly nine years in prison for transporting teenage girls for prostitution, with the judge reproving his exploitation of the vulnerable for profit.

A sheriff's vehicle crashed while transporting an inmate, Juliette Espinoza, who attempted to escape, causing minor injuries; the inmate now faces additional escape charges.

Los Peñasquitos Canyon has reopened with caution expressed for wet trails and damaged bridges. Visitors are urged to stay on existing paths to protect the environment and minimize habitat degradation.

"Fat Leonard" Francis appeared in a San Diego court after his arrest in Venezuela, with his defense attorneys seeking to withdraw, potentially delaying his sentencing further.

Desserts by Clément opens in Pacific Beach, offering classic French pastries, and promising a vibrant dining experience with a playful, polished café interior.

San Diego's Architectural Salvage is closing after nearly 30 years, with a final sale from January 12-14. Owner Elizabeth Scalice reflects on the store's impact and prepares for new ventures.