UPMC doctors and county lab tests say medetomidine — a veterinary sedative called "rhino tranq" — is now common in Pittsburgh's fentanyl, complicating overdose care.

A cadet at the Allegheny County Jail was charged after police say guns and suspected narcotics were seized at a Pittsburgh home. Investigations and court action are pending.

A Sandy Lake Township house fire early Thursday killed a mother and two children, the Mercer County coroner said.

Two people were charged after a planned gun sale in a Connellsville church parking lot turned violent. One person was shot in the head and is expected to survive.

DNA from a preserved 1989 rape kit led to the arrest of a 65-year-old Aliquippa man in Reserve Township. A preliminary hearing is scheduled for April 30.

Castle Biosciences is expanding at Nova Place on Pittsburgh’s North Side, with market reporting and company filings showing a phased increase in lab and office space. The move bolsters Nova Place’s role as a growing life‑sciences campus.

A Baltimore nonprofit bought the Pittsburgh Post‑Gazette, averting a May shutdown and keeping the city’s largest newsroom operating under a nonprofit model.

Highs near 83°F Tuesday with gusty southwest winds and two windows for thunderstorms; record-challenging warmth may arrive Wednesday. Plan for a blustery, wet commute.

Two-year-old Sarah Darji was found unresponsive inside a Pleasant Hills home; Allegheny County police have opened a death investigation and the medical examiner will determine cause.

Showers likely Monday with gusty southwest winds; stronger storms and record heat are possible midweek. Keep outdoor plans flexible.

Sunny, warm Sunday in Pittsburgh with highs near 80°F. Showers and thunderstorms are likely Monday; midweek may push temperatures into the low-to-mid 80s.

Two adults were arrested after one flashed a gun at children near Pittsburgh King PreK-8; no shots were fired and the student was not harmed.

A 16‑story downtown office tower at 411 Seventh Ave has been placed into receivership after refinancing failed and Duquesne Light arranged a large relocation, raising the prospect of a sale or restructuring.