The Christ Hospital trial will test a diabetes drug on 120 patients with chest pain but no blocked arteries, starting this fall.

New Cincinnati studios have lost 145 square feet since 2016, even as two-bedroom units buck the national trend.

Logan Stone died after a Lincoln Navigator hit his Acura from behind as traffic slowed for passing police cruisers.

Cincinnati’s heat ramps up from 94 Monday to 97 Thursday before storms finally return Friday. The weekend brings a modest cooldown.

The comedian, once dubbed “Prozac with a head” by Robin Williams, headlines the historic downtown venue October 4.

Bethany House and Urban Sites want to turn a Hamilton County office complex into homes for families who need three-bedroom units.

He waded in Friday night to grab a remote-control boat and never came back up, Hamilton County deputies say.

A lone driver was pulled from the East Fork Little Miami River near Dry Run Road and flown to UC Medical Center.

The Lebanon Planning Commission has approved plans to raze the shuttered Columbus Avenue diner, joining a regional wave of Frisch's teardowns.

Cincinnati’s calm Sunday starts a four-day heat climb, with 98 degrees possible Wednesday before late-week storm chances return.

Crystal Rains, 32, died after a Chevrolet Cruze flipped on Shaker Road. The driver never stopped.

Party on the Plaza starts at 6 pm with food trucks and a live DJ before the racing blockbuster hits Fraze Pavilion's new screen at sunset.

Jason Chadwick faces felonious assault charges after allegedly striking a man with his car on Wooded Ridge Drive.