Iovance’s Navy Yard plant turns tumors into Amtagvi, the first FDA-approved TIL therapy for melanoma, creating jobs and raising access questions.

A bright fireball flashed over New Jersey and Pennsylvania on Tuesday afternoon; videos circulated and experts say spring often brings an uptick in fireball sightings.

Penn Engineering launched a $200M Futures Fund to seed early‑stage research and spinouts and says it already has sizable early commitments to support climate, AI and biotherapeutics.

PJM says transmission work won’t be done until 2031, clashing with Constellation’s 2027 target to restart the former Three Mile Island unit under a Microsoft power deal.

P. Roy and Diana Vagelos donated $83.9 million to Penn Arts & Sciences — the school’s largest gift — to fund chemistry fellowships and energy research.

Amazon’s cuts and new research show AI is already changing hiring; Philadelphia workers and training programs are racing to adapt. Local entry-level roles are most exposed.

A new ranking places Philadelphia among the nation’s top startup cities, and local funding data and university-led funds suggest investment is beginning to return. The result highlights Philly’s durability and lower costs for founders.

A Penn–Harvard team embedded an ultrathin electronic mesh into pancreatic organoids, boosting cell maturity and glucose responsiveness.

One year after CHOPs first personalized CRISPR case, hospital leaders want to scale the approach into a platform for other rare pediatric diseases. Early signs are promising but major hurdles remain.

Alveus Therapeutics extended its Series A to $197M and moved its U.S. headquarters to Philadelphia to accelerate development of its obesity drug programs.

A 20-year-old patient treated at CHOP says a new FDA‑approved CRISPR therapy left him pain‑free, highlighting a local step in sickle‑cell care.

Temple University approved its strategic plan "Forward with Purpose," which sets the university's goals for 2034, emphasizing student success, research, and community impact.

SEPTA has updated Philadelphia's transit line names, using letters and colors for easier recognition, with strong public acceptance and continued communication to ease the transition.