Bay Area/ San Francisco/ Retail & Industry
Published on November 13, 2023
Amazon-Owned One Medical Opens New Castro Office & Closes AnotherPhoto: Steven Bracco/Hoodline

Amazon-owned One Medical has opened its newest medical office in SF's Castro neighborhood at 2355 Market Street, formerly home to Coldwell Banker.

Earliest this summer, Hoodline broke the news that One Medical would be taking over the long-vacant space.

Coldwell Banker closed this office in 2019, and since that time the space has remained vacant.

Inside One Mecial's new Castro medical offices at 2355 Market St. | Photo: One Medical


At the time it was unlcear if One Medical's offices at 595 Castro Street and 2175 Market Street (just two blocks down) would also remain open. Now a sign in the window at the Castro Street offices announced the location would be closing.

One Medical did not respond to Hoodline's request for comment.

"Our Castro office is relocating, our Castro care team will be moving with us to 2355 Market St.," the sign reads. The office officially closed Friday, November 10.

According to its website, One Medical's Castro office will be open Monday to Friday from 8 a.m. to 6 p.m. and closed on Saturday and Sunday.

One Medical is a membership-based practice that offers a full range of primary and pediatric care. In exchange for a yearly fee, patients receive perks like same-day appointments and the ability to talk one-on-one with doctors via email or video.

One Medical's offices at 595 Castro St. are now closed. | Photo: Steven Bracco/Hoodline


One Medical has over 200 locations nationwide, but because medical offices are exempt from formula retail rules, the company doesn't need to obtain a conditional use permit.

Amazon acquired One Medical last year for a reported $3.9 billion.

One Medical originally applied to convert the space to a medical office in October 2022 and had its permits reapproved in December 2022.

"Re-approvals usually occur in cases like this when plans change due to DBI requirements and are sent back to us to ensure that our approval still stands," SF Planning spokesperson Dan Sider previously told Hoodline.

At approximately 10,880 square feet, One Medical's new office fills one of the Castro's largest ground-floor storefront vacancies.

Public records obtained by Hoodline show building permits were approved in March. One Medical estimated the cost of building out the space at $1,472,000.

Permits for demolition, installing a fire sprinkler system, and installing an electrical sign were also issued. The additional permits were estimated at a total cost of $80,000.

One Medical's opening fills one of many ground-floor storefront vacancies along the 2300 block of Market St.

One Medical's offices at 2175 Market St. | Photo: Steven Bracco/Hoodline


Last month, men's clothing store Entour moved from its 16th Street location, into the former home decor shop Kenneth Wingard at 2319 Market Street.

In September, Mexican restaurant Zona Rosa opened in the former Tacorgasmico space.

Earlier this year, concept boutique Mikroblack (2323 Market) opened and Mistr Pharmacy is headed for 2301 Market.

The block currently has four vacancies: the spaces formerly occupied by Wells Fargo (2308 Market), Worn Out West (2354 Market), Bisou (2367 Market), and Pottery Barn (2390 Market) all remain vacant.

A new tenant for the 595 Castro St. space has not been announced. Prior to One Medical, the space was home to Fidelity National Title Company.