The Castro's newest cannabis retail store, Flore Store (258 Noe), is now open while historic neighborhood restaurant Flore (formerly Cafe Flore) has remained shuttered for two years.

Over the holiday weekend, multiple Castro neighborhood bars and restaurants announced they would be temporarily closed due to the recent surge of Covid-19 infections brought on by the Omicron variant.

The restoration of the Castro's nearly 25-year-old The Hope For the World Cure mural at 16th and Market streets could be impossible after recently being defaced by graffiti.

Longtime Castro Merchants administrator Richard Magary died Tuesday, December 20. Magary was 81.

A new cannabis retail shop has been proposed at 2057 Market St., formerly Market Nail Spa.

Keanu Reeves, Carrie-Anne Moss, Lana Wachowski, and the cast of The Matrix: Resurrections are set to descend on the Castro for the US premiere of the fourth installment of the Matrix franchise at the historic Castro Theatre.

The Castro's new 12-room boutique hotel, the Hotel Castro (4230 18th St.), is set to open just in time for New Year's Eve.

A mural painted in honor of former San Francisco Supervisor Harvey Milk on the exterior of Castro nightclub The Cafe (2369 Market St.) has been painted over.

The era of San Francisco Patrol Special Police officers patrolling the Castro is set to conclude at the end of the year with the departure of current officer Cody Clements.

Last week the Planning Commission unanimously approved the demolition and redevelopment of 240-250 Church Street, which previously housed 24-hour diner Sparky's, and continues to house decade-old bakery Thorough Bread and Pastry.

The Castro's newest Italian restaurant Vico Cavone officially opens this weekend in the former Firewood space at 4248 18th Street, after two weeks of a soft opening.

"We buy gay stuff," reads a sign at the base of the stairs leading up to Auto Erotica — which celebrated 25 years in the Castro this month.

An art gallery opens, a new pizza spot is on the way, and a fitness studio is moving.