A global tech failure involving Microsoft and CrowdStrike caused major disruptions to flights, banking, and media, as well as 911 services across several regions.

The article discusses the debate and details surrounding the Kids Online Safety Act (KOSA), aiming to protect children online, with both support and concerns about its potential effects on free speech.

Eli Lilly's drug tirzepatide, branded as Zepbound and Mounjaro, has shown a 94% reduction in the risk of type 2 diabetes development, and sustained weight loss in adults with pre-diabetes and obesity.

Eli Lilly introduces discounted single-dose vials of its obesity drug Zepbound, aiming to improve affordability and access for patients without insurance.

Overdose Lifeline premiered a documentary for youth drug prevention at Phoenix Theatre Cultural Center, offering a realistic view on substance experimentation risks rather than just saying no.

Marian University study finds risky behaviors such as binge drinking and drug use prevalent among U.S. medical students, with calls for better mental health support.

DHS launched a website, 'Worst of the Worst,' for public search of removed criminal illegal aliens, praised by Rep. Michelle Davis for promoting safety and transparency.

BOAH confirmed HPAI at a Boone County turkey farm affecting about 18,763 birds; control and surveillance zones are now in place and nearby farms will be tested.

Indiana Donor Network used an in‑house ex‑vivo lung perfusion system to rehabilitate lungs rejected elsewhere, enabling a transplant that saved a local man.

IU researchers show that sampling the right water pools removes puzzling isotope mismatches and could sharpen drought and water‑use forecasts for crops and ecosystems.

Sen. Todd Young says Indiana's new federal drone test‑site designation has manufacturers lining up to test tech and could spur manufacturing and biomanufacturing jobs.

Gov. Mike Braun announced a $1 billion pledge to expand central Indiana’s life‑sciences and ag ecosystem, saying it could support as many as 100,000 jobs.

Indianapolis‑based Eli Lilly says retatrutide met a Phase‑3 diabetes endpoint with notable A1c and double‑digit weight drops at 40 weeks, while more safety and regulatory steps remain.

Eli Lilly will buy Boston‑based Centessa for about $6.3B, adding an orexin agonist program led by cleminorexton. The deal pays $38 per ADS up front and could reach $47 with milestones.

A Lumina–Gallup study finds 47% of students have seriously considered changing majors because of AI, while 57% use AI weekly and many campus policies remain unclear.

Eric Christopher, the co-founder of Zylo, will take over as TechPoint’s president and CEO on April 7, stepping into a statewide role focused on talent, capital and AI. The hire follows a national search and the departure of Ting Gootee to CICP.

Gov. Mike Braun toured Ossium Health’s Indianapolis bone‑marrow bank as the state spotlights a $1 billion life‑sciences growth plan.

Indiana University physicians were co‑authors on a NEJM trial showing enfortumab vedotin plus pembrolizumab produced large survival gains for certain bladder cancer patients. IU sites helped enroll and analyze the data behind the finding.

A federal appeals court revived Teva’s patent fight with Eli Lilly and sent the case back to Massachusetts, reopening a dispute that once produced a $176.5M jury award.

Franciscan Alliance is moving to build an osteopathic medical school in Crown Point, with leadership roles posted and campus work already under way.

Eli Lilly is reportedly in advanced talks to buy Boston‑based Kelonia Therapeutics for more than $2 billion, folding a promising in‑vivo CAR‑T program into Lilly’s pipeline.

Carmel will pilot Qwake’s C‑THRU AR helmets this summer — 16 helmets and four command tablets in a three‑year, $375K program funded with help from the Heroes Club.

Eli Lilly agreed to buy Ajax Therapeutics for up to $2.3 billion, taking on a Cambridge biotech's experimental Type II JAK2 drug for myelofibrosis with data due in 2026.

Gov. Mike Braun and business leaders launched IN AI, a statewide hub and roadshows to help Hoosier employers use human-centered AI to increase productivity and wages.

Mounjaro's Q1 sales topped Keytruda, lifting Lilly's revenue and reshaping the blockbuster drug ranking.

Sam Schmidt converted the old Five Seasons club into a 114,000‑sq‑ft DRIVEN Neuro Recovery Center in Carmel, pairing deep‑water therapy, robotic gait trainers and nonprofit care. The campus aims to offer long‑term rehab beyond typical insurance limits.

A new Crossroads Academic Medical Institute launched in Indianapolis to coordinate clinical training across the state and widen access to care. Universities and hospital systems will share sites and curricula.

Eli Lilly says its experimental drug retatrutide produced near‑surgical levels of weight loss in late‑stage trials, but analysts note higher side effects and access questions.

A 12‑year‑old Center Grove student is the first in Indiana to receive an FDA‑approved gene therapy at Riley, a treatment that could end her monthly transfusions.

A Baylor‑led consortium's AllFaith Benchmark finds major language models often omit religious perspectives in ethics answers and show conversion biases. The work is open‑sourced for developers and scholars.

Riley Hospital at IU Health used cryopreserved marrow from a deceased donor in a world‑first pediatric transplant, putting a 14‑year‑old with leukemia into remission.